In 1998 researchers of the Medbiopharm Company developed the industrial technology of milk protein iodination. The name of the product is Iodcasein, it is safe, and even 1000 times  physiological norm exceeding does not leads to side effects. The safety and physiology of the preparation is resulted from follows: Iodine is included in protein through tyrosine residues producing monoiodotyrosine and diiodotyrosine. Active Iodine inclusion in tyrosine benzene ring occurs only if Iodine is in cation form. Use of iodine chloride which has Iodine in the mentioned form for casein iodizing allows excluding the use of oxidizers and provides almost maximum Iodine inclusion in proteins.

Iodcasein as Iodine source has a number of advantages in comparison with non organic Iodine compounds. It is more stable to external impacts, has longer shelf-life, and in addition, being thermostable, can be used in products which undergo thermal processing.

Use of Iodcasein for the prophylaxis of iodine deficient diseases allows to decrease the probability of overdosing, which can lead to hyperthyroid conditions.  Iodine split from iodothyrosines in human organism happens under specific enzyme action – deiodase, which restrict the formation of exceed iodides absorbed by thyroid.

Property of iodine metabolism regulation, when iodine enters in protein compound, discovered by specialists of Medbiopharm Company underline patents.